Evaluation of the Short-Term Efficacy of Transdermal Ozone Therapy in Turkish Patients with Internal Derangement of the Temporomandibular Joint

Öznur Özalp, Nelli Yıldırımyan, Alper Sindel, Mehmet Ali Altay, Reha Şükrü Kişnişci

Abstract


Objective:To investigate the efficacy of transdermal high-frequency ozone therapy in the management of pain and pain-related restricted jaw movements in patients with internal derangement of the temporomandibular joint (TMJ). Material and Methods:This retrospective study included 40 patients who had received transdermal high-frequency ozone therapy for the management of disc displacement with reduction of the TMJ. Subjects were treated 3 times for one week with a bio-oxidative high-frequency ozone generator with an intensity of 80% for ten minutes bilaterally.  Pain scores and maximal interincisal opening (MIO) values of the patients were evaluated before and after the treatment. Results:An increase in the mean MIO value was achieved following the ozone therapy, however, the difference was not statistically significant (p=0.350). A statistically significant decrease in the mean pain score (48.13 ± 27.75) was observed following the ozone therapy. Conclusion:Transdermal application of high frequency ozone may be a good alternative for management of pain and pain-related restricted jaw movements in patients with internal derangement of the TMJ.

Keywords


Temporomandibular Joint Disorders; Facial Pain; Ozone; Administration, Cutaneous.

Full Text:

PDF

References


Carrara SV, Conti PCR, Barbosa JS. Statement of the 1st consensus on temporomandibular disorders and orofacial pain. Dental Press J Orthod 2010; 15(3):114-20.

https://doi.org/10.1590/S2176-94512010000300014

Ingawalé S, Goswami T. Temporomandibular joint: Disorders, treatments, and biomechanics. Ann Biomed Eng 2009; 37(5):976-96. https://doi.org/10.1007/s10439-009-9659-4

Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP, et al. Diagnostic criteria for temporomandibular disorders (DC/TMD) for clinical and research applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Groupdagger. J Oral Facial Pain Headache 2014; 28(1):6-27. https://doi.org/10.11607/jop.1151

Zhang C, Wu JY, Deng DL, He BY, Tao Y, Niu YM, et al. Efficacy of splint therapy for the management of temporomandibular disorders: A meta-analysis. Oncotarget 2016; 7(51):84043-53. https://doi.org/10.18632/oncotarget.13059

Gauer RL, Semidey MJ. Diagnosis and treatment of temporomandibular disorders. Am Fam Physician 2015; 91(6):378-86.

Young AL. Internal derangements of the temporomandibular joint: A review of the anatomy, diagnosis, and management. J Indian Prosthodont Soc 2015; 15(1):2-7.

https://doi.org/10.4103/0972-4052.156998

Jin LJ, Lamster IB, Greenspan JS, Pitts NB, Scully C, Warnakulasuriya S. Global burden of oral diseases: emerging concepts, management and interplay with systemic health. Oral Dis 2016; 22(7):609-19. https://doi.org/10.1111/odi.12428

Wilkes CH. Internal derangements of the temporomandibular joint. Pathological variations. Arch Otolaryngol Head Neck Surg 1989; 115(4):469-77.

Hall MB, Brown RW, Baughman RA. Histologic appearance of the bilaminar zone in internal derangement of the temporomandibular joint. Oral Surg Oral Med Oral Pathol 1984; 58(4):375-81.

Paesani D, Westesson PL, Hatala M, Tallents RH, Kurita K. Prevalence of temporomandibular joint internal derangement in patients with craniomandibular disorders. Am J Orthod Dentofacial Orthop 1992; 101(1):41-7. https://doi.org/10.1016/0889-5406(92)70080-T

Tuncer AB, Ergun N, Tuncer AH, Karahan S. Effectiveness of manual therapy and home physical therapy in patients with temporomandibular disorders: A randomized controlled trial. J Bodyw Mov Ther 2013; 17(3):302-8. https://doi.org/10.1016/j.jbmt.2012.10.006

Sindel A, Uzuner F, Sindel M, Tozoglu S. Comparison of the efficiency of irrigation of single and double-needle techniques of temporomandibular joint arthrocentesis: A cadaver study. Cranio 2017; 35(6):405-9. https://doi.org/10.1080/08869634.2017.1279825

McGuire TP, Rittenberg BN, Baker GI. Surgery for disorders of the temporomandibular joint. Oral Health 2005; 95(7):51-66.

Butts R, Dunning J, Pavkovich R, Mettille J, Mourad F. Conservative management of temporomandibular dysfunction: A literature review with implications for clinical practice guidelines (Narrative review part 2). J Bodyw Mov Ther 2017; 21(3):541-8. https://doi.org/10.1016/j.jbmt.2017.05.021

Celakil T, Muric A, Gokcen Roehlig B, Evlioglu G, Keskin H. Effect of high-frequency bio-oxidative ozone therapy for masticatory muscle pain: A double-blind randomised clinical trial. J Oral Rehabil 2017; 44(6):442-51. https://doi.org/10.1111/joor.12506

Daif ET. Role of intra-articular ozone gas injection in the management of internal derangement of the temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 113(6):e10-4. https://doi.org/10.1016/j.tripleo.2011.08.006

Doğan M, Özdemir Doğan D, Düger C, Özdemir Kol İ, Akpınar A, Mutaf B, et al. Effects of high-frequency bio-oxidative ozone therapy in temporomandibular disorder-related pain. Med Princ Pract 2014; 23(6):507-10. https://doi.org/10.1159/000365355

Gupta G, Mansi B. Ozone therapy in periodontics. J Med Life 2012; 5(1):59-67.

Seidler V, Linetskiy I, Hubálková H, Stanková H, Smucler R, Mazánek J. Ozone and its usage in general medicine and dentistry. A review article. Prague Med Rep 2008; 109(1):5-13.

Vaillant JD, Fraga A, Díaz MT, Mallok A, Viebahn-Hänsler R, Fahmy Z, et al. Ozone oxidative postconditioning ameliorates joint damage and decreases pro-inflammatory cytokine levels and oxidative stress in PG/PS-induced arthritis in rats. Eur J Pharmacol 2013; 714(1-3):318-24. https://doi.org/10.1016/j.ejphar.2013.07.034

Pressman S, Warburg OH. The story of ozone. Plasmafire, 2000.

Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, et al. Therapeutic effects of topical application of ozone on acute cutaneous wound healing. J Korean Med Sci 2009; 24(3):368-74. https://doi.org/10.3346/jkms.2009.24.3.368

Rahimi-Movaghar V, Eslami V. The major efficient mechanisms of ozone therapy are obtained in intradiscal procedures. Pain Physician 2012; 15(6):E1007-8.

Manoto SL, Maepa MJ, Motaung SK. Medical ozone therapy as a potential treatment modality for regeneration of damaged articular cartilage in osteoarthritis. Saudi J Biol Sci 2018; 25(4):672-9. https://doi.org/10.1016/j.sjbs.2016.02.002

McNeely ML, Olivo SA, Magee DJ. A systematic review of the effectiveness of physical therapy interventions for temporomandibular disorders. Phys Ther 2006; 86(5):710-25.

Çapan N. Physical therapy modalities, exercise and postoperative rehabilitation in temporomandibular joint disorders. Turkish J Phys Med Rehab 2010; 56(1):15-8. https://doi.org/10.4274/tftr.56.15 [In Turkish]

Lang AM. Botulinum toxin therapy for myofascial pain disorders. Curr Pain Headache Rep 2002; 6(5):355-60.

Al-Ani Z, Gray RJ, Davies SJ, Sloan P, Glenny A-M. Stabilization splint therapy for the treatment of temporomandibular myofascial pain: A systematic review. J Dent Educ 2005; 69(11):1242-50.

Gezer İA, Levendoğlu F. Temporomandibular eklem rahatsızlıklarının sınıflandırılması, tanı ve tedavisi. Genel Tip Dergisi 2016; 26(1):34-40. https://doi.org/10.15321/GenelTipDer.2016118200 [In Turkish]

Bocci V. Ozone as Janus: This controversial gas can be either toxic or medically useful. Mediators Inflamm 2004; 13(1):3-11. https://doi.org/10.1080/0962935062000197083

Michelotti A, Steenks MH, Farella M, Parisini F, Cimino R, Martina R. The additional value of a home physical therapy regimen versus patient education only for the treatment of myofascial pain of the jaw muscles: Short-term results of a randomized clinical trial. J Orofac Pain 2004; 18(2):114-25.

Wright EF, North SL. Management and treatment of temporomandibular disorders: A clinical perspective. J Man Manip Ther 2009; 17(4): 247-54. https://doi.org/10.1179/106698109791352184

Armijo-Olivo S, Pitance L, Singh V, Neto F, Thie N, Michelotti A. Effectiveness of manual therapy and therapeutic exercise for temporomandibular disorders: Systematic review and meta-analysis. Phys Ther 2016; 96(1):9-25. https://doi.org/10.2522/ptj.20140548

Carmeli E, Sheklow SL, Bloomenfeld I. Comparative study of repositioning splint therapy and passive manual range of motion techniques for anterior displaced temporomandibular discs with unstable excursive reduction. Physiotherapy 2001; 87(1):26-36. https://doi.org/10.1016/S0031-9406(05)61189-3

Iliakis E, Petropoulos I, Iliaki A, Agapitos E, Agrogiannis G. Is medical ozone safe when injected intra-articularly? A comparative histological study in rat. Int J Ozone Ther 2008; 7(1):7-15.

Rather LJ. Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus. Bull N Y Acad Med 1971; 47(3):303-22.

Teresa B, Wolanska E, Cieszko-Buk M, Orlowski M, Chalas R. Practical use of ozone in dentistry - Comments. Ann Univ Mariae Curie Sklodowska Lubin Polonia 2008; 63:28.

Matsumura K, Miura K, Takata Y, Kurokawa H, Kajiyama M, Abe I, et al. Changes in blood pressure and heart rate variability during dental surgery. Am J Hypertens 1998; 11(11):1376-80. https://doi.org/10.1016/S0895-7061(98)00157-5




DOI: http://dx.doi.org/10.4034/PBOCI.2019.191.44

PBOCI IS A MEMBER OF CROSSREF AND ALL THE CONTENT OF ITS JOURNALS ARE LINKED BY DOIS THROUGH CROSSREF.