Evaluation of the Short-Term Efficacy of Transdermal Ozone Therapy in Turkish Patients with Internal Derangement of the Temporomandibular Joint

Öznur Özalp, Nelli Yıldırımyan, Alper Sindel, Mehmet Ali Altay, Reha Şükrü Kişnişci


Objective:To investigate the efficacy of transdermal high-frequency ozone therapy in the management of pain and pain-related restricted jaw movements in patients with internal derangement of the temporomandibular joint (TMJ). Material and Methods:This retrospective study included 40 patients who had received transdermal high-frequency ozone therapy for the management of disc displacement with reduction of the TMJ. Subjects were treated 3 times for one week with a bio-oxidative high-frequency ozone generator with an intensity of 80% for ten minutes bilaterally.  Pain scores and maximal interincisal opening (MIO) values of the patients were evaluated before and after the treatment. Results:An increase in the mean MIO value was achieved following the ozone therapy, however, the difference was not statistically significant (p=0.350). A statistically significant decrease in the mean pain score (48.13 ± 27.75) was observed following the ozone therapy. Conclusion:Transdermal application of high frequency ozone may be a good alternative for management of pain and pain-related restricted jaw movements in patients with internal derangement of the TMJ.


Temporomandibular Joint Disorders; Facial Pain; Ozone; Administration, Cutaneous.

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DOI: http://dx.doi.org/10.4034/PBOCI.2019.191.44