Screening of Essential Oils Antifungal Activity on Candida Strains

Ricardo Dias de CASTRO, Edeltrudes de Oliveira LIMA

Abstract


bucal; Candida; Plantas Medicinais.
Objective: The purpose of this study was to identify the antifungal activity of essential oils on Candida strains involved in oral cavity infections.
Methods: essential oils obtained from the following species were evaluated: Citrus reticulata (Cravo Tangerine) Citrus aurantifolia (Tahiti Lime), Cinnamomum zeylanicum (Cinnamon), Matricaria chamomilla (Blue Chamomile), Mentha piperita (Mint), Eugenia uniflora (Pitanga) and Zingiber officinale (Ginger). The determination of antifungal activity was performed using the diffusion technique on solid medium, where filter paper discs were soaked in oils and placed in Petri dishes containing Sabouraud dextrose agar inoculated with strains of Candida albicans and C. tropicalis. It was also observed the minimum inhibitory concentration from the microdilution method. Tests were performed in duplicate.
Results: We observed significant antifungal activity of essential oils of C. zeylanicum, C. aurantifolia and M. piperita, which had halos of microbial growth inhibition with diameters up to 48 mm, 30 mm and 19 mm, respectively. Still, it was possible to identify that 66.7% of strains tested were resistant to essential oils of C. reticulata, M. chamomilla, E. uniflora and Z. officinale. C. zeylanicum and nystatin showed μg mL-1 and 32 μg mL-1 MIC, respectively.
Conclusion: The essential oils tested have antifungal activity, with best results for C. zeylanicum. It is suggested to conduct other tests for evaluation of anti-Candida activity of this essential oil, which could represent possible therapeutic agent in the treatment of fungal infections of the oral cavity.

Keywords


Candidíase bucal; Candida; Óleo essencial



DOI: http://dx.doi.org/10.4034/pboci.v11i3.888

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