INCIDENCE OF NOSOCOMIAL INFECTIONS BY GRAM-NEGATIVE NON-FERMENTERS AND PROFILE OF ANTIMICROBIAL SENSITIVITY IN A HOSPITAL IN CAMPINA GRANDE-PB

Abstract

The non-fermenting bacilli (BGN-NF) are frequent hospital microorganisms and cause disease by infecting colonization in immunocompromised patients or when they reach sterile body sites through invasive hospital procedures such as introduction of catheters and ventilators, are therefore considered opportunistic bacteria. This work aimed study the epidemiology and antimicrobial resistance of BGN-NF, isolated from infectious process of patients admitted in a public hospital in Campina Grande-PB, in the period April 2009 to March 2011. Of the 1,056 patients analyzed cultures from different clinical specimens, 358 (33.9 %) presented bacterial growth and were classified as cases of community infections (IC) or hospital infections (IH), according to the criteria established by the Law 2616/98 from the Brazilian Ministry of Health, noting 52 (15%) cases of infection by rods BGN-NF. Among these, Pseudomonas aeruginosa was most prevalent species with 44 (84.6%) of insulation,especially also for high resistance to antimicrobials. The largest number of P. aeruginosa, was detected in secretions collected orotracheal tube with 9 (26.4%) cases, with prevalence in patients above 60 years. Among the hospital enrironments where these microorganisms were more prevalent, the intensive care unit, with 44.2% of cases. There was a high resistance of strains of P. aeruginosa from most of the antimicrobials tested. Among those who showed good antimicrobial activity, stood out: imipenen with 2 (5.8%) and ciprofloxacin and amikacin 7 (20.5%) with drug-resistant strains. Not observed difference in resistance between nosocomial and/or communitary strains.