Periodontal Tissue Condition on Systemic Lupus Erythematosus Patients: A Clinical Study

Authors

  • Nanda Rachmad Putra Gofur
  • Nurdiana Nurdiana
  • Kusworini Handono
  • Handono Kalim

Keywords:

Lupus Erythematosus, Systemic, Periodontal Diseases, Periodontitis

Abstract

Objective: To evaluate periodontal tissue condition on systemic lupus erythematosus (SLE) patients and its characteristics. Material and Methods: This descriptive and cross-sectional study involved 61 SLE patients. Clinical examination of the oral cavity was performed using periodontal index (PI), gingival index (GI), clinical attachment loss (CAL) and number of loose teeth. Also, we evaluated SLE duration, treatment duration, ethnics, marital status, educational background, family income, and occupation. Results: In the evaluation of periodontal tissue, 93.4% had bleeding on probing, 80.3% clinical attachment loss, and 16.3% loose teeth. A total of 54 patients (88.5%) with SLE had periodontitis. Seven subjects had no periodontitis, 11 mild periodontitis, 29 moderate periodontitis and 14 severe periodontitis. Mean Periodontal Index score, Gingival Index, Clinical Attachment Loss (mm), and the number of mobility teeth, Plaque Index  and Calculus Index respectively were 2.66 ± 1.20, 1.95 ± 1.02, 0.75 ± 0.59 mm, 1,49 ± 1.77. There was a significant difference in periodontal index score, shown periodontitis between employment and unemployment subjects (p=0.004) and a moderate correlation between periodontitis and occupation. Conclusion: Periodontitis found as manifestations SLE patients, followed by bleeding on probing and loose teeth. Its characteristics is playing a role in periodontitis in SLE patients.

References

Nazir MA. Prevalence of periodontal disease, its association with systemic diseases and prevention. Int J Health Sci 2017; 11(2):72-80.

Lang NP, Bartold PM. Periodontal health. J Periodontol 2018; 89(Suppl 1):S9-S16. https://doi.org/10.1002/JPER.16-0517

Novak MJ, Novak KF. Chronic Periodontitis. In: Newman MG, Takei H, Klokkevoid PR, Carranza FA. Carranza’s Clinical Periodontology. 11th. ed. Missouri: Saunders Elsevier; 2012. pp. 160-164, 320-323.

Salama R, Sadaie M, Hoare M, Narita M. Cellular senescence and its effector programs. Genes Dev 2014; 28(2):99- 114. https://doi.org/10.1101/gad.235184.113

Rutter-Locher Z, Fuggle N, Orlandi M, D’Aiuto F, Sofat N. Periodontal Disease and Autoimmunity: What We Have Learned from Microbiome Studies in Rheumatology. In: Arjunan P. Periodontitis: A Useful Reference. London: IntechOpen; 2017. pp. 113-141.

Detert J, Pischon N, Burmester GR, Buttgereit F. The association between rheumatoid arthritis and periodontal disease. Arthritis Res Ther 2010; 12(5):218. https://doi.org/10.1186/ar3106

Rees F, Doherty M, Grainge MJ, Lanyon P, Zhang W. The worldwide incidence and prevalence of systemic lupus erythematosus: a systematic review of epidemiological studies. Rheumatology 2017; 56(11):1945-61. https://doi.org/10.1093/rheumatology/kex260

Wu YD, Lin CH, Chao WC, Liao TL, Chen DY, Chen HH. Association between a history of periodontitis and the risk of systemic lupus erythematosus in Taiwan: a nationwide, population-based, case-control study. PLoS One 2017; 12(10):e0187075. https://doi.org/10.1371/journal.pone.0187075

Kaur G, Mohindra K, Singla S. Autoimmunity – basics and link with periodontal disease. Autoimmun Rev 2017; 16(1):64-71. https://doi.org/10.1016/j.autrev.2016.09.013

Yucel-Lindberg T, Bage T. Inflammatory mediators in the pathogenesis of periodontitis. Expert Rev Mol Med 2013; 15:e7. https://doi.org/10.1017/erm.2013.8

Chadna S, Bathla M. Stress and periodontium: a review of concept. J Oral health Comm Dent 2010; 4:17-22.

Taba Jr M, Souza SLS, Mariguela VC. Periodontal disease: a genetic perspective. Braz Oral Res 2012; 26(Suppl 1):32- 38. https://doi.org/10.1590/S1806-83242012000700006

Wankhede AN, Wankhede SA, Wasu SP. Role of genetic in periodontal disease. J Int Clin Dent Res Organ 2017; 9(2):53-8. https://doi.org/10.4103/jicdro.jicdro_10_17

Kuhn A, Bonsmann G, Anders HJ, Herzer P, Tenbrock K, Schneider M. The diagnosis and treatment of systemic lupus erythematosus. Dtsch Arztebl Int 2015; 112(25):423-32. https://doi.org/10.3238/arztebl.2015.0423

Boraschi D1, Aguado MT, Dutel C, Goronzy J, Louis J, Grubeck-Loebenstein B, et al. The gracefully aging immune system. Sci Transl Med 2013; 5(185):185ps8. https://doi.org/10.1126/scitranslmed.3005624

Haynes L, Lefebvre JS. Age-related deficiencies in antigen-specific CD4 T cell responses: lessons from mouse models. Aging Dis 2011; 2(5):374-81.

Lerang K, Gilboe IM, Steinar Thelle D, Gran JT. Mortality and years of potential life loss in systemic lupus erythematosus: a population-based cohort. Lupus 2014; 23(14):1546-52. https://doi.org/10.1177/0961203314551083

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Published

2022-03-17

How to Cite

Gofur, N. R. P. ., Nurdiana, N. ., Handono, K. ., & Kalim, H. . (2022). Periodontal Tissue Condition on Systemic Lupus Erythematosus Patients: A Clinical Study. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 20, e5094 . Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/1059

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