The Use of Bio-Inks and the Era of Bioengineering and Tooth Regeneration

Authors

  • Saman Tauqir
  • Saqib Ali
  • Anand Marya

Keywords:

Regeneration, Bioengineering, Tooth, Stem Cells

Abstract

Objective: To review existing literature and provide an update on the current use of Bio-Inks and potential future use. Material and Methods: A MeSH keyword search was conducted to find out relevant articles for this short review. Results: Bio inks used in 3D printing grafting require various properties essential for the selection. Combining multiple methods and improved properties is essential for developing successful bio-inks for 3D grafting of functional tissues and tooth pulp regeneration from stem cells. To date, researchers have made many efforts to grow teeth based on stem cells and inculcate regeneration of teeth along with surrounding tissues like alveolar bones and periodontal ligaments. Conclusion: 3D printing with Bio-Inks requires strict adherence to safety protocols for successful outcomes, making it difficult to employ this routinely.

References

Hyde S, Dupuis V, Mariri BP, Dartevelle S. Prevention of tooth loss and dental pain for reducing the global burden of oral diseases. Int Dent J 2017; 67(Suppl 2):19-25. https://doi.org/10.1111/idj.12328

Greenstein G, Cavallaro J, Romanos G, Tarnow D. Clinical recommendations for avoiding and managing surgical complications associated with implant dentistry: a review. J Periodontol 2008; 79(8):1317-29. https://doi.org/10.1902/jop.2008.070067

Cassetta M, Pranno N, Calasso S, Di Mambro A, Giansanti M. Early peri-implant bone loss: a prospective cohort study. Int J Oral Maxillofac Surg 2015; 44(9):1138-45. https://doi.org/10.1016/j.ijom.2015.04.002

Duarte Campos DF, Zhang S, Kreimendahl F, Köpf M, Fischer H, Vogt M, et al. Hand-held bioprinting for de novo vascular formation applicable to dental pulp regeneration. Connect Tissue Res 2020; 61(2):205-15. https://doi.org/10.1080/03008207.2019.1640217

Han J, Kim DS, Jang H, Kim HR, Kang HW. Bioprinting of three-dimensional dentin-pulp complex with local differentiation of human dental pulp stem cells. J Tissue Eng 2019; 10:2041731419845849. https://doi.org/10.1177/2041731419845849

Nakao K, Morita R, Saji Y, Ishida K, Tomita Y, Ogawa M, et al. The development of a bioengineered organ germ method. Nat Methods 2007; 4(3):227-30. https://doi.org/10.1038/nmeth1012

Ono M, Oshima M, Ogawa M, Sonoyama W, Hara ES, Oida Y, et al. Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model. Sci Rep 2017; 7:44522. https://doi.org/10.1038/srep44522

AbdulQader ST, Kannan TP, Rahman IA, Ismail H, Mahmood Z. Effect of different calcium phosphate scaffold ratios on odontogenic differentiation of human dental pulp cells. Mater Sci Eng C Mater Biol Appl 2015; 49:225-33. https://doi.org/10.1016/j.msec.2014.12.070

Chalisserry EP, Nam SY, Park SH, Anil S. Therapeutic potential of dental stem cells. J Tissue Eng 2017; 8:2041731417702531. https://doi.org/10.1177/2041731417702531

Barone S, Neri P, Paoli A, Razionale AV. Design and manufacturing of patient-specific orthodontic appliances by computer-aided engineering techniques. Proc Inst Mech Eng H 2018; 232(1):54-66. https://doi.org/10.1177/0954411917742945

Marya A. Utilizing aligners to solve the COVID-19-affected orthodontic practice conundrum!. J Adv Oral Res 2020; 11(2):117-9. https://doi.org/10.1177/2320206820942400

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Published

2022-05-13

How to Cite

Tauqir, S. ., Ali, S. ., & Marya, A. . (2022). The Use of Bio-Inks and the Era of Bioengineering and Tooth Regeneration. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 22, e210184. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/1212

Issue

Vol. 22 (2022)

Section

Critical Review / Scope Review

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Copyright (c) 2022 Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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