Effect of Different Preparations of Fluoride Gel on Salivary pH of Albino Rats


  • Sadia Shakeel
  • Muhammad Sharjeel Ilyas
  • Ayesha Fahim
  • Amna Ahsan
  • Hina Majid
  • Mariam Ashraf
  • Naseem Akhter
  • Mohammad Khursheed Alam


Acidulated Phosphate Fluoride, Dental Caries, Saliva, Salivary Glands, Sodium Fluoride


Objective: To evaluate the effect of different preparations of fluoride gels on the salivary pH of albino rats. Material and Methods: This experimental study consisted of 40 Albino rats randomly divided into four equal groups. Group A was the control group and received no intervention. Experimental group B received a topical application of 0.2% sodium fluoride gel. Experimental group C received topical application of stannous fluoride gel 0.4%. Experimental group D received topical application of APF gel (1.23% acidulated phosphate fluoride gel). The different preparations of the gels were applied once daily for 4 minutes on the occlusal surface of the right maxillary molars for 14 days. Salivary pH values were recorded immediately after the application of gels with the help of pH paper on day 1 and day 14. Results: There was a significant difference in the pH level of groups B, C and D after 14 days of fluoride application (p < 0.05). The non-parametric Kruskal Wallis test was applied for the comparison between the groups. Conclusion: This study concluded that all the fluoride gels after administration caused the acidic pH of saliva with the most acidic effect produced by APF gel.


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How to Cite

Shakeel, S., Ilyas, M. S., Fahim, A., Ahsan, A., Majid, H., Ashraf, M., Akhter, N., & Alam, M. K. (2022). Effect of Different Preparations of Fluoride Gel on Salivary pH of Albino Rats. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 22, e210169. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/1591



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