Association between Dentin Hypersensitivity and Health/Oral Health-related Quality of Life: A Systematic Review and Meta-Analysis

Anna Rachel dos Santos Soares; Rayssa Soares Barbosa; Julya Ribeiro Campos; Loliza Luiz Figueiredo Houri Chalub; Allyson Nogueira Moreira; Raquel Conceição Ferreira

Authors

Anna Rachel dos Santos Soares
Rayssa Soares Barbosa
Julya Ribeiro Campos
Loliza Luiz Figueiredo Houri Chalub
Allyson Nogueira Moreira
Raquel Conceição Ferreira

Keywords:

Dentin Sensitivity, Quality of Life, Oral Health, Patient Reported Outcome Measures

Abstract

Objective: To investigate the association between DH and Health (HRQoL) or Oral Health-Related Quality of Life (OHRQoL). Material and Methods: PubMed, Web of Science, Scopus, EMBASE, Cochrane, Scielo, LILACS/BBO, Biblioteca Digital de Teses e Dissertações (BDTD), Open Grey, and Google Scholar databases were screened in September 2019 (updated in October 2022). Observational studies were selected to compare HRQoL/OHRQoL(outcome) according to DH(exposure) or evaluate the association among these variables. Standardized Joanna Briggs Institute critical appraisal tool for analytical cross-sectional studies was used to analyze the risk of bias. A random-effects meta-analysis was conducted to synthesize evidence for the association between DH and OHRQoL. Results: 10 papers met inclusion criteria and were evaluated. In most studies, presenting or having a greater intensity of DH was associated with a negative impact on one's quality of life. However, most of these studies showed a moderate to high risk of methodological bias. The consistent finding from studies with a low risk of bias suggests a significant association between DH and OHRQoL. Meta-analysis was feasible for three studies with substantial heterogeneity. The pooled Odds Ratio was 2.14 (95%CI 1.15-3.99; I²=57,44%).Conclusion: Many studies presented a high risk of bias; therefore, the actual effect of DH on one's quality of life remains uncertain.

References

Zeola LF, Soares PV, Cunha-Cruz J. Prevalence of dentin hypersensitivity: Systematic review and meta-analysis. J Dent 2019; 81:1-6. https://doi.org/10.1016/j.jdent.2018.12.015

Blaizot A, Offner D, Trohel G, Bertaud V, Bou C, Catteau C, et al. Prevalence of sensitive teeth and associated factors: a multicentre, cross-sectional questionnaire survey in France. BMC Oral Health 2020; 20:1-10. https://doi.org/10.1186/s12903-020-01216-1

Splietch CH, Tachou A. Epidemiology of dentin hypersensitivity. Clin Oral Invest 2013; 17(Suppl 1):S3-S8. https://doi.org/10.1007/s00784-012-0889-8

Olley RC, Sehmi H. The rise of dentine hypersensitivity and tooth wear in an aging population. Br Dent J 2017; 223(4):293-7. https://doi.org/10.1038/sj.bdj.2017.715

West NX, Sanz M, Lussi A, Bartlett D, Bouchard P, Bourgeois D. Prevalence of dentine hypersensitivity and study of associated factors: A European population-based cross-sectional study. J Dent 2013; 41(10):841-51. https://doi.org/10.1016/j.jdent.2013.07.017

Alcântara PM, Barroso NFF, Botelho AM, Douglas-de-Oliveira DW, Gonçalves PF, Flecha OD. Associated factors to cervical dentin hypersensitivity in adults: a transversal study. BMC Oral Health 2018; 18(1):1-6. https://doi.org/10.1186/s12903-018-0616-1

Porritt JM, Sufi F, Barlow A, Baker SR. The role of illness beliefs and coping in the adjustment to dentine hypersensitivity. J Clin Periodontol 2014; 41(1):60-9. https://doi.org/10.1111/jcpe.12177

Siou JL. How to make a link between Oral Health-Related Quality of Life and dentin hypersensitivity in the dental office? Clin Oral Investig 2013; 17(Suppl 1):S41-44. https://doi.org/10.1007/s00784-012-0915-x

Bekes K, Hirsch C. What is known about the influence of dentine hypersensitivity on oral health-related quality of life? Clin Oral Investig 2013; 17(Suppl 1):45-51. https://doi.org/10.1007/s00784-012-0888-9

Bekes K, John MT, Schaller HG, Hirsch C. Oral health-related quality of life in patients seeking care for dentin hypersensitivity. J Oral Rehabil 2009; 36(1):45-51. https://doi.org/10.1111/j.1365-2842.2008.01901.x

Melo TL, Silva MJCN, Sousa BM, Freitas SAA, Pereira EM, Pereira AFV. Sensibilidade da dentina e o impacto na qualidade de vida de pacientes com periodontite crônica da Universidade Federal do Maranhão. Arq Odontol 2015; 51(4):179-85. [In Portuguese].

Goh V, Corbet EF, Leung WK. Impact of dentine hypersensitivity on oral health-related quality of life in individuals receiving supportive periodontal care. J Clin Periodontol 2016; 43(7):595-602. https://doi.org/10.1111/jcpe.12552

Wagner TP, Costa RSA, Rios FS, Moura MS, Maltz M, Jardim JJ, et al. Gingival recession and oral health-related quality of life: a population-based cross-sectional study in Brazil. Community Dent Oral Epidemiol 2016; 44(4):390-9. https://doi.org/10.1111/cdoe.12226

Masud M, Al-Bayaty FH, Muhamed NAH, Alwi AS, Takiyudin Z, Hidayat MFH. Gingival recession and dentine hypersensitivity in periodontal patients: Is it affecting their oral health related quality of life?. J Int Dent Medical Res 2017; 10(3):909-914.

Basaran S, Celik C. Turkish adaptation of Dentine Hypersensitivity Experience Questionnaire (DHEQ). Community Dent Health 2018; 35(1):47-51. https://doi.org/10.1922/CDH_4151Basaran05

Midwood I, Davies M, Newcombe RG, West N. Patients’ perception of their oral and periodontal health and its impact. A cross-sectional study in the NHS. Br Dent J 2019; 227(7):587-93. https://doi.org/10.1038/s41415-019-0721-9

Yılmaz M, Oduncuoğlu BF, Nişancı Yılmaz MN. Evaluation of patients’ perception of gingival recession, its impact on oral health-related quality of life, and acceptance of treatment plan. Acta Odontol Scand 2020; 78(6):454-62. https://doi.org/10.1080/00016357.2020.1758773

Soares ARDS, Chalub LLFH, Barbosa RS, Campos DEP, Moreira AN, Ferreira RC. Prevalence and severity of non-carious cervical lesions and dentin hypersensitivity: association with oral-health related quality of life among Brazilian adults. Heliyon 2021; 7(3):e06492. https://doi.org/10.1016/j.heliyon.2021.e06492

Ni Riordain R, Glick M, Al Mashhadani SSA, Aravamudhan K, Barrow J, Cole D, et al. Developing a standard set of patient-centred outcomes for adult oral health - an international, cross-disciplinary consensus. Int Dent J 2021; 71(1):40-52. https://doi.org/10.1111/idj.12604

Silveira MF, Marôco JP, Freire RS, Martins AMEB, Marcopito LF. Impact of oral health on physical and psychosocial dimensions: an analysis using structural equation modeling. Cad Saúde Pública 2014; 30(6):1169-82. https://doi.org/10.1590/0102-311X00072013

Santana MJ, Haverman L, Absolom K, Takeuchi E, Feeny D, Grootenhuis M, et al. Training clinicians in how to use patient-reported outcome measures in routine clinical practice. Qual Life Res 2015; 24(7):1707-18. https://doi.org/10.1007/s11136-014-0903-5

Zucoloto ML, Marôco J, Campos JADB. Impact of oral health on health-related quality of life: a cross-sectional study. BMC Oral Health 2016; 16(1):1-6. https://doi.org/10.1186/s12903-016-0211-2

Baiju RM, Peter E, Varghese N, Anju P. Patient reported outcome assessment of periodontal therapy: a systematic review. J Clin Diagn Res 2017; 11(8):ZC14-ZC9. https://doi.org/10.7860/JCDR/2017/28505.10343

Page M J, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021; 372:n71. https://doi.org/10.1136/bmj.n71

Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, et al. Chapter 7: Systematic reviews of etiology and risk. In: Aromataris E, Munn Z (Editors). Joanna Briggs Institute Reviewer's Manual. The Joanna Briggs Institute; 2017. Available from https://reviewersmanual.joannabriggs.org/ [Accessed on October 8, 2019].

Esteves CV, de Campos WG, Amorim Dos Santos J, Kobayashi Velasco S, Guerra ENS, Siqueira WL, et al. Proteomic profile of saliva collected directly from ducts: a systematic review. Clin Oral Investig 2020;

(2):559-68. https://doi.org/10.1007/s00784-019-03165-8

Lee JY, Watt RG, Williams DM, Giannobile WV. A New definition for oral health: Implications for clinical practice, policy, and research. J Dent Res 2017; 96(2):125-7. https://doi.org/10.1177/0022034516682718

Mokkink LB, de Vet HCW, Prinsen CAC, Patrick DL, Alonso J, Bouter LM, et al. COSMIN risk of bias checklist for systematic reviews of Patient‐Reported Outcome Measures. Qual Life Res 2017; 27(5):1171-1179. https://doi.org/10.1007/s11136‐017‐1765‐4

Prinsen CAC, Mokkink LB, Bouter LM, Alonso J, Patrick DL, De Vet HC, et al. COSMIN guideline for systematic reviews of Patient‐Reported Outcome Measures. Qual Life Res 2018; 27(5):1147-57. https://doi.org/10.1007/s11136-018-1798-3

Terwee CB, Prinsen CAC, Chiarotto A, Westerman MJ, Patrick DL, Alonso J, et al. COSMIN methodology for evaluating the content validity of patient-reported outcome measures: a Delphi study. Qual Life Res 2018; 27(5):1159-70. https://doi.org/10.1007/s11136-018-1829-0

Idon PI, Esan TA, Bamise CT. Oral health‑related quality of life in patients presenting with dentine hypersensitivity: A randomized controlled study of treatment effect. Eur J Gen Dent 2017; 6:99-105. https://doi.org/10.4103/ejgd.ejgd_9_17

Dekkers OM, Vandenbroucke JP, Cevallos M, Renehan AG, Altman DG, Egger M. COSMOS-E: Guidance on conducting systematic reviews and meta-analyses of observational studies of etiology. PLoS Med 2019; 16(2):e1002742. https://doi.org/10.1371/journal.pmed.1002742