Factors Associated with Hyposalivation in Brazilian Adults


  • Handerson Nunes de Carvalho
  • Yuri Lins dos Santos
  • Kenio Costa de Lima
  • Ítalo de Macedo Bernardino
  • Ana Flávia Granville-Garcia
  • Ramon Targino Firmino
  • Edja Maria Melo de Brito Costa


Prevalence, Epidemiology, Salivation, Hyposalivation, Xerostomia


Objective: To determine the occurrence of hyposalivation in Brazilian adults and its association with individual determinants, such as the use of medications, systemic conditions, smoking, and alcohol consumption. Material and Methods: A cross-sectional study with 402 adults was developed. Information was collected on sociodemographic and general health characteristics, and sialometry was performed with stimulated salivary flow. It indicated low salivary flow when ≤ 0.7 mL/min. Bivariate and multivariate analyses were conducted using a decision tree (p<0.05). Results: The sample was comprised predominantly of women (68.2%) aged ≤ 29 years (25.4%). Most participants did not use medication (56.7%). Among systemic diseases, the most cited was hypertension (25.1%). More than a third of the participants presented hyposalivation (40.3%), being associated with the following variables: age between 50 to 59 years (p=0.011), female sex (p<0.001), menopause (p=0.001), use of alcohol (p=0.033), systemic disease (p=0.002) and medication use (p<0.001). In multivariate analysis, in addition to sex (p<0.001) and hypertension (p=0.005), an association was also found between hyposalivation and diabetes (p=0.014). Conclusion: Factors associated with hyposalivation in adults were sex and the presence of hypertension or diabetes.


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How to Cite

de Carvalho, H. N., dos Santos, Y. L., de Lima, K. C., Bernardino, Ítalo de M., Granville-Garcia, A. F., Firmino, R. T., & Costa, E. M. M. de B. (2023). Factors Associated with Hyposalivation in Brazilian Adults. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 24, e220006. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/2955



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