Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion

Noura Alessa; Shahzad Ali Shah; Rishibha Bhardwaj; Prabu Mahin Syed Ismail; M. Nazargi Mahabob; Prashant Babaji; Vardarajula Venkata Ramaiah

Authors

Noura Alessa
Shahzad Ali Shah
Rishibha Bhardwaj
Prabu Mahin Syed Ismail
M. Nazargi Mahabob
Prashant Babaji
Vardarajula Venkata Ramaiah

Keywords:

Dental Caries, Efficiency, Dental Enamel, Ozone

Abstract

Objective: To assess the efficacy of bioactive glass, self-assembling peptide, and ozone-remineralizing agents on the artificial carious lesion. Material and Methods: On the extracted 60 premolar teeth, an artificial carious lesion/demineralization was created. Later, the remineralization of demineralized teeth was done with respective remineralizing agents (Group A: Calcium sodium phosphosilicate (bioactive glass), Group B: Self-assembling peptide, Group C: Ozone remineralizing agents and Group D (Control): De ionized water. The degree of demineralization and remineralization were evaluated using the Vickers Hardness Number. Results: There was a decrease in microhardness from baseline to demineralization in all the groups, and this reduction was found to be statistically considerable. After the remineralization of demineralized samples with respective remineralizing agents, there was an increase in microhardness of 312.38, 276.67, and 254.42 in groups A, B, and C, respectively. In contrast, in Group D, there were no changes. Conclusion: Bioactive glass and self-assembling peptides had higher remineralizing capacities, which can be used to treat early carious lesions.

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