Qualitative Analysis of Baltic Amber Resin by Gas Chromatography Coupled with Mass Spectrometry and the Therapeutic Potential of this Fossil Resin

Manuela Soares Raposo; Fernanda Michel Tavares Canto; Raquel Vieira Santana da Silva; Débora de Almeida Azevedo; Ivete Pomarico Souza; Matheus Melo Pithon

Authors

Manuela Soares Raposo
Fernanda Michel Tavares Canto
Raquel Vieira Santana da Silva
Débora de Almeida Azevedo
Ivete Pomarico Souza
Matheus Melo Pithon

Keywords:

Amber, Chromatography, Mass Spectrometry

Abstract

Objective: To analyze the molecular composition of a sample of Baltic amber taken from an amber bracelet, verify the presence or absence of compounds beneficial to human health, and discuss the therapeutic potential of this fossil resin. Material and Methods: For this, a qualitative analysis was performed by gas chromatography coupled with mass spectrometry (GC-MS system), which can perform an automated separation into individual components of amber. Results: The samples comprised terpenes and terpenoids: monoterpenoids, sesquiterpenoids, diterpenoids, hydronaphthalene, succinic acid, and isopimaric acid. These have therapeutic potential for several diseases, inhibit several stages of the inflammatory process, and improve the symptoms caused by it. Conclusion: The amber of this sample tested is formed by terpenes and terpenoids, substances with anti-inflammatory and analgesic. However, an in-depth study is needed on the release and absorption of substances in human skin or their actual effectiveness.

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