Evaluation of the Effect of the Intensity and Occurrence of Postoperative Pain of Resin-Based and Bioceramic Root Canal Sealers: A Systematic Review and Meta-Analysis of Randomized Controlled Trial Studies


  • Samira Jamali
  • Maryam Darvish
  • Navid Nasrabadi
  • Sara Jafarizadeh


Endodontics, Root Canal Filling Materials, Pain, Postoperative


Objective: To evaluate resin- and bioceramic root canal sealers affect postoperative intensity and pain occurrence. Material and Methods: From the electronic databases, PubMed, Cochrane Library, Embase, ISI have been used to perform systematic literature until September 2020. Electronic titles were managed using the Endnote X8 software. They performed searches with mesh terms. Two reviewers blindly and independently extracted data from studies that included data for data extraction. Results: A total of 186 potentially relevant titles and abstracts were found. Finally, four studies were included. Pain score was (RR = -0.20; 95% CI -1.09–0.68; p= 0.65). This result showed no statistically significant difference for the resin-based and bioceramic root canal sealers after 24 hours between the VAS scores. Conclusion: Postoperative pain was low in Patients requiring root canal retreatment and obturated with resin-based or bioceramic-based sealers without extrusion beyond the apex. No differences were observed between postoperative pain in resin-based and bioceramic root canal sealers 24 and 48 hours postoperatively.


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How to Cite

Jamali, S. ., Darvish, M. ., Nasrabadi, N. ., & Jafarizadeh, S. (2021). Evaluation of the Effect of the Intensity and Occurrence of Postoperative Pain of Resin-Based and Bioceramic Root Canal Sealers: A Systematic Review and Meta-Analysis of Randomized Controlled Trial Studies. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 21, e0219. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/703



Systematic Reviews (and Meta-Analysis)