Comparison of Microscopic Endodontic Techniques: A Systematic Review and Meta-Analysis


  • Samira Jamali
  • Robab Farhang
  • Navid Nasrabadi
  • Hashem Ahmadizadeh
  • Elnaz Mousavi
  • Mehrzad Kaviani


Endodontics, Microscopy, Root Canal Filling Materials


Objective: To evaluate the success rates of resin-based endodontic surgery (RES) and endodontic microsurgery (EMS), and compare their results. Material and Methods: A total of 19 and 34 full-text papers were reviewed, and finally, 2 and 6 studies were selected for RES and EMS, respectively. The stages of the study selection process were illustrated in Figure 1. The demographic characteristics were also described using the IBM SPSS Software, and the meta-analysis was fulfilled via Stata V.14. Results: A total number of 811 teeth were analyzed in this systematic review and meta-analysis, with a mean follow-up of 38.63 months. Besides, the results of the meta-analysis indicated that both methods not only differed in terms of implementation but also produced varying outcomes. Accordingly, EMS demonstrated a higher success rate likelihood with a significant difference from that of RES. Conclusion: An excellent proof was made available through this meta-analysis regarding the resin-based endodontic surgery success rate likelihood (79.9%) and an update for the endodontic microsurgery success rate possibility (100%).


Setzer FC. Endodontic microsurgery - A technique for the 21st century. J Orofac Sci 2018; 10(1):1-2.

Rubinstein RA, Kim S. Short-term observation of the results of endodontic surgery with the use of a surgical operation microscope and Super-EBA as root-end filling material. J Endod 1999; 25(1):43-8.

Kim S, Kratchman S. Modern endodontic surgery concepts and practice: a review. J Endod 2006; 32(7):601-23.

Floratos S, Kim S. Modern endodontic microsurgery concepts: a clinical update. Dent Clin North Am 2017; 61(1):81-91.

Wang M, Ren X, Pan Y. Micro-computed tomography-based anatomical study of the branch canals in mandibular anterior teeth in a Chinese population. Clin Oral Investig 2019; 23(1):81-86.

Taschieri S, Del Fabbro M, Testori T, Weinstein R. Microscope versus endoscope in root-end management: a randomized controlled study. Int J Oral Maxillofac Surg 2008; 37(11):1022-6.

Wang Z-H, Zhang M-M, Wang J, Jiang L, Liang Y-H. Outcomes of endodontic microsurgery using a microscope and mineral trioxide aggregate: a prospective cohort study. J Endod 2017; 43(5):694-8.

Jensen S, Nattestad A, Egdø P, Sewerin I, Munksgaard E, Schou S. A prospective, randomized, comparative clinical study of resin composite and glass ionomer cement for retrograde root filling. Clin Oral Investig 2002; 6(4):236-43.

Tsesis I, Faivishevsky V, Kfir A, Rosen E. Outcome of surgical endodontic treatment performed by a modern technique: a meta-analysis of literature. J Endod 2009; 35(11):1505-11.

Song M, Nam T, Shin S-J, Kim E. Comparison of clinical outcomes of endodontic microsurgery: 1 year versus long-term follow-up. J Endod 2014; 40(4):490-4.

Christiansen R, Kirkevang LL, Hørsted-Bindslev P, Wenzel A. Randomized clinical trial of root-end resection followed by root-end filling with mineral trioxide aggregate or smoothing of the orthograde gutta-percha root filling-1-year follow-up. Int Endod J 2009; 42(2):105-14.

Kim E, Song J-S, Jung I-Y, Lee S-J, Kim S. Prospective clinical study evaluating endodontic microsurgery outcomes for cases with lesions of endodontic origin compared with cases with lesions of combined periodontal-endodontic origin. J Endod 2008; 34(5):546-51.

Shinbori N, Grama AM, Patel Y, Woodmansey K, He J. Clinical outcome of endodontic microsurgery that uses EndoSequence BC root repair material as the root-end filling material. J Endod 2015; 41(5):607-12.

Zhou W, Zheng Q, Tan X, Song D, Zhang L, Huang D. Comparison of mineral trioxide aggregate and iRoot BP plus root repair material as root-end filling materials in endodontic microsurgery: a prospective randomized controlled study. J Endod 2017; 43(1):1-6.

von Arx T, Hänni S, Jensen SS. Clinical results with two different methods of root-end preparation and filling in apical surgery: mineral trioxide aggregate and adhesive resin composite. J Endod 2010; 36(7):1122-9.

Rud J, Rud V, Munksgaard E. Periapical healing of mandibular molars after root-end sealing with dentine-bonded composite. Int Endod J 2001; 34(4):285-92.




How to Cite

Jamali, S. ., Farhang, R. ., Nasrabadi, N. ., Ahmadizadeh, H. ., Mousavi, E. ., & Kaviani, M. . (2021). Comparison of Microscopic Endodontic Techniques: A Systematic Review and Meta-Analysis. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 21, e5414. Retrieved from



Systematic Reviews (and Meta-Analysis)