What are the Systemic Factors Associated with the Molar-Incisor Hypomineralization Etiology?


  • Gabriela Fonseca-Souza
  • Aluhê Lopes Fatturi
  • Fabian Calixto Fraiz
  • Luciana Reichert da Silva Assunção
  • Juliana Feltrin-Souza


Epidemiology, Tooth Abnormalities, Dental Enamel Hypoplasia, Molar


Objective: To evaluate the systemic factors associated with Molar-Incisor Hypomineralization (MIH) etiology. Material and Methods: A total of 731 8-year-old schoolchildren enrolled in the public school system in Curitiba, Brazil, was randomly selected. The MIH diagnosis was performed by calibrated examiners (Kappa >0.80) according to the European Academy of Pediatric Dentistry criteria (2003). The systemic factors were collected through a semi-structured questionnaire and applied to the children’s mothers, addressing the medical history from pregnancy to the first three years of children’s life. Associations were analyzed by Poisson regression analysis with robust variance (p<0.05). Results: The systemic factors in the prenatal and perinatal periods were not associated with MIH (p>0.05). The children who used medications during the first years of life had a significantly higher prevalence of MIH (PRc = 2.18 CI = 95% 1.06–4.48; p=0.033). Conclusion: The use of medications during the first three years of children’s life is associated with a higher prevalence of MIH.


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How to Cite

Fonseca-Souza, G. ., Fatturi, A. L. ., Fraiz, F. C. ., Assunção, L. R. da S. ., & Feltrin-Souza, J. . (2021). What are the Systemic Factors Associated with the Molar-Incisor Hypomineralization Etiology?. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 21, e0041. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/763



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