Efficacy of Oil Pulling in the Management of Oral Submucous Fibrosis: A Preliminary Study

Authors

  • Swatantra Shrivastava
  • Shushma Gurumurthy
  • Bharati Doni
  • Ruchi Agrawal
  • Santosh Rayagouda Patil
  • Hesham Shokry Ismail
  • Mohammad Khursheed Alam

Keywords:

Oral Submucous Fibrosis, Precancerous Conditions, Therapeutics

Abstract

Objective: To evaluate the effectiveness of oil pulling in the management of oral submucous fibrosis (OSMF). Material and Methods: A total of 62 patients clinically and histopathologically diagnosed as OSMF were incorporated in the present study. The subjects are randomly divided equally into two groups, Group A (oil pulling group) and Group B (placebo group). Subjects in Group A were asked to perform OP with sesame oil on an empty stomach in the morning for 3 months and Group B was given placebo capsules for 3 months. Assessment of various clinical parameters was done regularly, and data were analyzed using the Chi-square test. Results: Eighty-two percent had a habit of betel nut chewing, while 18% of the patients had tobacco chewing habits, which were among the main causative factors for OSMF. Clinical improvements in mouth opening, tongue protrusion, difficulty in speech and deglutition, and burning sensation were significant in the Group A. None of the patients reported any discomfort or side effects. The symptoms were not severe in nature and resolved in few days without stopping the therapy. Conclusion: Oil pulling can bring about significant clinical improvements in the symptoms like a mouth opening and tongue protrusion.

References

Jiang X, Hu J. Drug treatment of oral submucous fibrosis: a review of the literature. J Oral Maxillofac Surg 2009; 67(7):1510-5. https://doi.org/10.1016/j.joms.2008.12.056

Cox SC, Walker DM. Oral submucous fibrosis. A review. Aust Dent J 1996; 41(5):294-9. https://doi.org/10.1111/j.1834-7819.1996.tb03136.x.

Pindborg JJ, Sirsat SM. Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol 1966; 22:764-79. https://doi.org/10.1016/0030-4220(66)90367-7

Fedorowicz Z, Chan Shih-Yen E, Dorri M, Nasser M, Newton T, Shi L. Interventions for the management of oral submucous fibrosis. Cochrane Database Syst Rev 2008; (4):CD007156. https://doi.org/10.1002/14651858.CD007156.pub2

Naseem M, Khiyani MF, Nauman H, Zafar MS, Shah AH, Khalil HS. Oil pulling and importance of traditional medicine in oral health maintenance. Int J Health Sci 2017; 11(4):65-70.

Hsu E, Parthasarathy S. Anti-inflammatory and antioxidant effects of sesame oil on atherosclerosis: a descriptive literature review. Cureus 2017; 9(7):e1438. https://doi.org/10.7759/cureus.1438

Patil S, Khandelwal S, Maheshwari S. Comparative efficacy of newer antioxidants spirulina and lycopene for the treatment of oral submucous fibrosis. Clin Cancer Investig J 2014; 3:482-6. https://doi.org/10.4103/2278-0513.142618

Canniff JP, Harvey W. The aetiology of oral submucous fibrosis: the stimulation of collagen synthesis by extracts of areca nut. Int J Oral Surg 1981; 10(Suppl 1):163-7.

Rajendran R. Oral submucous fibrosis: etiology, pathogenesis, and future research. Bull World Health Organ 1994; 72(6):985-96.

Khan S, Chatra L, Prashanth SK, Veena KM, Rao PK. Pathogenesis of oral submucous fibrosis. J Cancer Res Ther 2012; 8(2):199-203. https://doi.org/10.4103/0973-1482.98970

Yoithapprabhunath TR, Maheswaran T, Dineshshankar J, Anusushanth A, Sindhuja P, Sitra G. Pathogenesis and therapeutic intervention of oral submucous fibrosis. J Pharm Bioallied Sci 2013; 5(Suppl 1):S85-S88. https://doi.org/10.4103/0975-7406.113303

Dayal, Reddy R, Anuradha Bhat K. Malignant potential of oral submucous fibrosis due to intraoral trauma. Indian J Med Sci 2000; 54(5):182-7.

Patil S, Santosh BS, Maheshwari S, Deoghare A, Chhugani S, Rajesh PR. Efficacy of oxitard capsules in the treatment of oral submucous fibrosis. J Cancer Res Ther 2015; 11(2):291-4. https://doi.org/10.4103/0973-1482.136023

Patil S, Al-Zarea BK, Maheshwari S, Sahu R. Comparative evaluation of natural antioxidants spirulina and aloe vera for the treatment of oral submucous fibrosis. J Oral Biol Craniofac Res 2015; 5(1):11-5. https://doi.org/10.1016/j.jobcr.2014.12.005

Patil S, Halgatti V, Maheshwari S, Santosh BS. Comparative study of the efficacy of herbal antioxdants oxitard and aloe vera in the treatment of oral submucous fibrosis. J Clin Exp Dent 2014; 6(3):e265-70. https://doi.org/10.4317/jced.51424

Patil S, Maheshwari S. Efficacy of pentoxifylline in the management of oral submucous fibrosis. J Orofac Sci 2014; 6:94-8. https://doi.org/10.4103/0975-8844.143048

Deme P, Narasimhulu CA, Parthasarathy S. Identification and evaluation of anti-inflammatory properties of aqueous components extracted from sesame (Sesamum indicum) oil. J Chromatogr B Analyt Technol Biomed Life Sci 2018; 1087-1088:61-9. https://doi.org/10.1016/j.jchromb.2018.04.029

Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci 2017; 19(1):70. https://doi.org/10.3390/ijms19010070

Askari A, Ravansalar SA, Naghizadeh MM, Mosavat SH, Khodadoost M, Jazani AM, et al. The efficacy of topical sesame oil in patients with knee osteoarthritis: A randomized double-blinded active-controlled non-inferiority clinical trial. Complement Ther Med 2019; 47:102183. https://doi.org/10.1016/j.ctim.2019.08.017

Cox S, Zoellner H. Physiotherapeutic treatment improves oral opening in oral submucous fibrosis. J Oral Pathol Med 2009; 38(2):220-6. https://doi.org/10.1111/j.1600-0714.2008.00696.x

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Published

2021-11-17

How to Cite

Shrivastava, S., Gurumurthy, S. ., Doni, B. ., Agrawal, R. ., Patil, S. R. ., Ismail, H. S. ., & Alam, M. K. . (2021). Efficacy of Oil Pulling in the Management of Oral Submucous Fibrosis: A Preliminary Study. Pesquisa Brasileira Em Odontopediatria E Clínica Integrada, 21, e0218. Retrieved from https://revista.uepb.edu.br/PBOCI/article/view/765

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